Green tea polyphenols against renal disorders

  • Theertham P. Rao Nutritional Foods Division, Taiyo Kagaku Co., Ltd. Yokkaichi, Mie 510 0844 Japan
  • Lekh Raj Juneja Nutritional Foods Division, Taiyo Kagaku Co., Ltd. Yokkaichi, Mie 510 0844 Japan
  • Tsutomu , Okubo Nutritional Foods Division, Taiyo Kagaku Co., Ltd. Yokkaichi, Mie 510 0844 Japan
  • Djong-Chi Chu Nutritional Foods Division, Taiyo Kagaku Co., Ltd. Yokkaichi, Mie 510 0844 Japan
  • Takako Yokozawa Nutritional Foods Division, Taiyo Kagaku Co., Ltd. Yokkaichi, Mie 510 0844 Japan

Abstract

Green tea, exclusively rich in powerful antioxidant and active free radical scavenger polyphenols, is known for various therapeutic and prophylactic uses. The pharmacological functions of green tea polyphenols against chronic renal failure and related complications were examined in rat models and humans. The polyphenols were found effective in easing the pains concerned with renal failure. The application of polyphenols were improved the renal function by inhibiting the mesangial cells proliferation. The polyphenols have relieved the high oxidation stress condition and renal hypertension by inhibiting the production of oxidative uremic toxins and improving the renal blood circulating state, respectively. The antioxidant activities of green tea polyphenols against free radicals that are involved in the above complications have established the activity of green tea in regulating renal function.
Keywords: Antioxidant, glomerular function, glomerular sclerosis, green tea polyphenols renal hypertension, uremia

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How to Cite
Rao, T., L. Juneja, T. , Okubo, D.-C. Chu, and T. Yokozawa. “Green Tea Polyphenols Against Renal Disorders”. International Journal of Tea Science, Vol. 2, no. 01 and 02, June 2003, pp. 51-58, doi:10.20425/ijts.v2i1and2.4589.