Green Tea and its polyphenols, targeting signalling pathways for chemoprevention

  • Deepa Khanna Cardiovascular Pharmacology Division, Department of Pharmacology, Rajendra Institute of Technology and Sciences, Sirsa 125 055, Haryana, India
  • Monika Garg Cardiovascular Pharmacology Division, Department of Pharmacology, Rajendra Institute of Technology and Sciences, Sirsa 125 055, Haryana, India

Abstract

Tea polyphenols can protect against the multi-stages of cancer initiation, promotion, and progression. Research findings and epidemiologic studies suggest that the polyphenolic compounds, (-)-epigallocatechin-3-gallate (EGCG), (-)-epicatechin-3-gallate (ECG); (-)-epigallocatechin (EGC) and (-)-epicatechin (EC) found primarily in Green Tea have chemo-preventive potential. Cell signalling cascades and their interacting factors have become important targets of chemoprevention and phenolic phytochemicals and plant extracts seem to be promising in this endeavour.
Keywords: Green tea; Polyphenols; Signalling pathways; Chemoprevention; Cancer

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How to Cite
Khanna, D., and M. Garg. “Green Tea and Its Polyphenols, Targeting Signalling pathways for Chemoprevention”. International Journal of Tea Science, Vol. 9, no. 02 and 03, Oct. 2013, pp. 76-88, doi:10.20425/ijts.v9i2and3.4543.